Details for gene set NCI_SIGNALING BY AURORA KINASES[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	wtNotch
GeneSet	NCI_SIGNALING BY AURORA KINASES
Enrichment Score (ES)	0.56593204
Normalized Enrichment Score (NES)	1.6256886
Nominal p-value	0.0031847134
FDR q-value	0.20624186
FWER p-Value	0.896

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NCAPH	6220435	56	3.183	0.0471	Yes
2	NDEL1	2370465	94	2.900	0.0908	Yes
3	CHUK	7050736	113	2.821	0.1342	Yes
4	TPX2	6420324	306	2.306	0.1601	Yes
5	CUL3	1850520	446	2.066	0.1852	Yes
6	NSUN2	2120193	517	1.961	0.2123	Yes
7	RASA1	1240315	523	1.945	0.2426	Yes
8	UBE2D3	3190452	542	1.915	0.2718	Yes
9	NCL	2360463 4540279	591	1.866	0.2986	Yes
10	NDC80	4120465	867	1.583	0.3087	Yes
11	KIF23	5570112	1019	1.409	0.3227	Yes
12	CDCA8	2340286 6980019	1114	1.320	0.3384	Yes
13	CYLD	6590079	1155	1.276	0.3563	Yes
14	IKBKB	6840072	1212	1.233	0.3727	Yes
15	RIPK2	5050072 6290632	1265	1.187	0.3886	Yes
16	MAPK14	5290731	1301	1.150	0.4048	Yes
17	AURKA	780537	1317	1.140	0.4220	Yes
18	MAP3K14	5890435	1319	1.137	0.4398	Yes
19	GSK3B	5360348	1347	1.119	0.4560	Yes
20	INCENP	520593	1387	1.082	0.4709	Yes
21	BCL3	3990440	1412	1.061	0.4863	Yes
22	PPP2R5D	4010156 380408 5550112 5670162	1582	0.982	0.4927	Yes
23	TACC3	5130592	1848	0.814	0.4912	Yes
24	CENPA	5080154	1872	0.803	0.5026	Yes
25	BIRC5	110408 580014 1770632	1894	0.790	0.5139	Yes
26	BIRC2	2940435 4730020	1953	0.757	0.5227	Yes
27	MALT1	4670292	2066	0.685	0.5274	Yes
28	TRAF6	4810292 6200132	2133	0.654	0.5341	Yes
29	TNF	6650603	2136	0.652	0.5443	Yes
30	STMN1	1990717	2167	0.636	0.5527	Yes
31	SMC2	4810133	2389	0.548	0.5494	Yes
32	CPEB1	3190524	2427	0.533	0.5558	Yes
33	SMC4	5910240	2448	0.524	0.5630	Yes
34	AURKB	5890739	2647	0.458	0.5595	Yes
35	BCL10	2360397	2661	0.455	0.5659	Yes
36	MDM2	3450053 5080138	2893	0.375	0.5594	No
37	EVI5	6380040	2920	0.367	0.5638	No
38	REL	360707	3244	0.279	0.5507	No
39	NOD2	2510050	3324	0.261	0.5506	No
40	PPP1CC	6380300 2510647	3376	0.251	0.5518	No
41	TNFRSF1A	1090390 6520735	3542	0.215	0.5462	No
42	RELA	3830075	4082	0.138	0.5193	No
43	PIK3CA	6220129	4636	0.093	0.4909	No
44	ATM	3610110 4050524	4686	0.090	0.4897	No
45	IKBKG	3450092 3840377 6590592	4826	0.082	0.4835	No
46	KLHL13	6590731	5319	0.059	0.4579	No
47	TDRD7	6550520	5495	0.052	0.4493	No
48	JUB	5860711 5900500	5663	0.047	0.4410	No
49	SRC	580132	6242	0.031	0.4103	No
50	RAN	2260446 4590647	6789	0.019	0.3811	No
51	KIF2C	6940082	6866	0.018	0.3773	No
52	AKT1	5290746	7250	0.010	0.3568	No
53	PAK1	4540315	7429	0.008	0.3473	No
54	FBXW11	6450632	7458	0.007	0.3459	No
55	XPO1	540707	7753	0.002	0.3301	No
56	BUB1	5390270	8457	-0.009	0.2923	No
57	NPM1	4730427	9124	-0.020	0.2567	No
58	PIK3R1	4730671	9205	-0.022	0.2527	No
59	CBX5	3830072 6290167	9360	-0.024	0.2448	No
60	SGOL1	1980075 5220092 6020711	10214	-0.040	0.1994	No
61	DES	1450341	10230	-0.041	0.1992	No
62	SYK	6940133	10320	-0.042	0.1951	No
63	PSMA3	5900047 7040161	10440	-0.045	0.1894	No
64	ARHGEF7	1690441	10801	-0.054	0.1708	No
65	AURKC	4060687	11384	-0.069	0.1405	No
66	BRCA1	4780669	11972	-0.090	0.1102	No
67	ERC1	1580170 2630717 6110762 6840280	12462	-0.111	0.0856	No
68	MYLK	4010600 7000364	13035	-0.144	0.0570	No
69	KIF20A	2650050	13526	-0.183	0.0334	No
70	PRKCA	6400551	13971	-0.229	0.0131	No
71	VIM	20431	14039	-0.235	0.0132	No
72	TNFAIP3	2900142	15056	-0.405	-0.0353	No
73	RACGAP1	3990162 6620736	15208	-0.437	-0.0366	No
74	TP53	6130707	15236	-0.442	-0.0310	No
75	GADD45A	2900717	15472	-0.512	-0.0357	No
76	PRKACA	2640731 4050048	15991	-0.708	-0.0525	No
77	OAZ1	110181	16022	-0.724	-0.0427	No
78	NFKB1	5420358	16242	-0.822	-0.0416	No
79	RHOA	580142 5900131 5340450	16637	-0.998	-0.0471	No
80	NFKB2	2320670	16799	-1.069	-0.0390	No
81	LCK	3360142	16840	-1.087	-0.0240	No
82	NFKBIA	1570152	16859	-1.101	-0.0076	No
83	RELB	1400048	17499	-1.525	-0.0181	No
84	CDC25B	6940102	17519	-1.538	0.0051	No
85	ARRB2	2060441	18568	-3.434	0.0026	No